Research Mission: IEHS researchers share a common bond: To understand the basic biology and molecular mechanisms that are responsible for the emergence and progression of environmentally-linked disease in the urban landscape   

IEHS Director and Professor

Melissa Runge-Morris, MD
Transcriptional regulation of the sulfotransferase xenobiotic metabolizing enzymes; implications for the developmental of metabolic disease and cancer

IEHS Faculty 

Joseph A. Caruso, PhD, Assistant Professor
Applications of proteomics approaches to biological research; proteomics profiling and biomarker discovery 
Ye-Shi Ho, PhD, Professor
Transgenic animal models applied to dissect oxidative stress mechanisms
Hyesook Kim, PhD, Adjunct Faculty
President of Detroit R&D, Inc.; Commercial innovations in environmental research    
Thomas A Kocarek, PhD, Professor
Endogenous metabolites of the mevalonate/cholesterol/bile acid pathway as modulators of liver gene expression and function
Xiangyi Lu, PhD, Associate Professor
Mechanisms of environmental sensing by the eukaryotic cilium, a cellular sensory organelle. Drosophila melanogaster and mammalian ciliopathic disease models for ciliopathies such as polycystic kidney disease 

John J. Reiners, PhD, Professor
Molecular and cellular mechanisms of neurological, developmental and respiratory disease; impact of environmental  factors

Douglas M. Ruden, PhD, Professor
Role of epigenetic signaling as a determinant of environmental  disease 
Paul M. Stemmer, PhD, Associate Professor
Director of Proteomics Core Facility, Wayne State University ;  Analysis of the proteome for biomarker discovery and mechanistic research   
Gan Wang, PhD, Associate Professor
DNA repair mechanisms in cancer development and progression 

Tracie Baker, DVM, Ph.D. Assistant Professor
The Baker Lab is focused on multidisciplinary, translational research that bridges human, animal and environmental health. and environmental health.